Product Overview
Blocking/Immunizing peptide for anti-Bradykinin receptor B1 antibody
Target
Bradykinin receptor B1
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Function
G-protein coupled receptor activity; bradykinin receptor activity; peptide binding; receptor activity; signal transducer activity;
Synonyms
BDKRB1; bradykinin receptor B1; B1 bradykinin receptor; B1BKR; BKR1; bradyb1; BK-1 receptor; bradykinin receptor 1; bradykinin B1 receptor; B1R; BKB1R; BRADYB1;
Citations
Publication ()
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