Bex1 is a signaling adapter molecule involved in p75NTR/NGFR signaling. It is thought to play a role in cell cycle progression and neuronal differentiation. Bex1 inhibits neuronal differentiation in response to nerve growth factor (NGF). Bex1 has also been implicated as a tumor suppressor.
Function
RNA polymerase II activating transcription factor binding;
Synonyms
BEX1; brain expressed, X-linked 1; BEX2; HBEX2; HGR74-h; protein BEX1; brain-expressed X-linked protein 1; ovarian granulosa cell 13.0 kDa protein hGR74;
Citations
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