Tag/Conjugate
Unconjugated
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function
ATP binding; actin binding;
Synonyms
ACTR2; ARP2 actin-related protein 2 homolog (yeast); ARP2; actin-related protein 2; actin-like protein 2;
Citations
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MCCARTHY, SA; TURLEY, H; et al. MONOCLONAL-ANTIBODIES THAT RECOGNIZE THE TYPE-2 ACTIVIN RECEPTOR, ACTR2. HYBRIDOMA 13:199-203(1994).
MCCARTHY, SA; BICKNELL, R; et al. ACTIVIN-A BINDS TO A HETEROTRIMERIC RECEPTOR COMPLEX ON THE VASCULAR ENDOTHELIAL-CELL SURFACE - EVIDENCE FOR A TYPE-3 ACTIVIN RECEPTOR. JOURNAL OF BIOLOGICAL CHEMISTRY 269:3909-3912(1994).