Anti-stage-specific embryonic antigen-3 monoclonal antibody (DMAB28381)

Rat anti-Mouse stage-specific embryonic antigen-3 monoclonal antibody for IHC, FC Datasheet

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Specifications


Host Species
Rat
Antibody Isotype
IgM
Clone
ND-742
Species Reactivity
Mouse
Immunogen
4-8 cell stage mouse embryos
Conjugate
Unconjugated

Target


Alternative Names
Stage specific embryonic antigen4antibody; Rat Anti-stage-specific embryonic antigen-3 Monoclonal Antibody; Anti-stage-specific embryonic antigen-3 Monoclonal Antibody; stage-specific embryonic antigen-3 Monoclonal Antibody Rat Anti-stage-specific embryon

Product Background


Antigen Description
SSEA3 is a globoseries carbohydrate antigen present on both cell surface glycolipids and glycopeptides. It is found on the surface of mouse oocytes, becoming restricted to the intracellular mass of the early blastocyst and then to the primitive endoderm. It is present on the surface of human teratocarcinoma cells (EC), embryonic germ cells (EG) and embryonic stem cells (ES) but not mouse undifferentiated mouse cells of these types. SSEA3 expression decreases as human EC, ES and EG cells differentiate but increases on differentiation of mouse EC, ES and EG cells. It is also found on the surface of mouse erythrocytes.

Citations


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References


TIPPETT, P; ANDREWS, PW; et al. RED-CELL ANTIGEN-P (GLOBOSIDE) AND ANTIGEN-LUKE - IDENTIFICATION BY MONOCLONAL-ANTIBODIES DEFINING THE MURINE STAGE-SPECIFIC EMBRYONIC ANTIGEN-3 AND ANTIGEN-4 (SSEA-3 AND SSEA-4). VOX SANGUINIS 51:53-56(1986).
DASGUPTA, S; HOGAN, EL; et al. CHEMICAL AND IMMUNOLOGICAL CHARACTERIZATION OF GALACTOSYL-BETA-1-3-GLOBOSIDE IN BOVINE, HUMAN, AND RAT-BRAIN. JOURNAL OF NEUROCHEMISTRY 65:2344-2349(1995).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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