Anti-ZNF274 monoclonal antibody, clone 5D23

Antibody Isotype

IgG2b

Clone

5D23

Species Reactivity

Human

Immunogen

ZNF274 (AAH09763.1, 420 a.a. ~ 530 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

ZNF274; zinc finger protein 274; neurotrophin receptor-interacting factor homolog; ZKSCAN19; zinc finger protein zfp2; zinc finger protein HFB101; KRAB zinc finger protein HFB101; zinc finger protein with KRAB and SCAN domains 19; ZF2; HFB101; FLJ37843; D

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.

Pathway

Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem; p75(NTR)-mediated signaling, organism-specific biosystem;