A synthesized peptide derived from human ZFYVE20, corresponding to a region within the internal amino acids.
Conjugate
Unconjugated
Applications
Application Notes
WB 1:500-1:1000 IF/ICC 1:100-1:500
General Notes
This product (Catalog No. DPABH-05030) is a rabbit-derived polyclonal antibody raised against human ZFYVE20. This antibody exhibits cross-reactivity with ZFYVE20 from mouse and rat. It has been affinity purified by Protein A. Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3). Plays a role in the recycling of transferrin receptor to the plasma membrane. DPABH-05030 is suitable for use in WB 1 (500-1:1000), IF/ICC 1 (100-1:500) applications. DPABH-05030 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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