antigen sequence, corresponding to amino acids 745-874 of Human FOG2.
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50 - 1/200.
Target
Alternative Names
ZFPM2; zinc finger protein, FOG family member 2; DIH3; FOG2; ZNF89B; hFOG-2; ZC2HC11B; zinc finger protein ZFPM2; FOG-2; Friend of GATA2; friend of GATA 2; zinc finger protein 89B; friend of GATA protein 2; zinc finger protein, multitype 2; transcription
Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2.
Pathway
Factors involved in megakaryocyte development and platelet production; MicroRNAs in cancer.
Citations
Publication ()
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