ZFP90 (ZFP90 zinc finger protein) is a protein-coding gene. Diseases associated with ZFP90 include optic atrophy, and paraplegia, and among its related super-pathways are Gene Expression. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and DNA binding. An important paralog of this gene is ZNF79. May function as a repressor or silencer protein, and most likely exerts its repressing activity upon zinc-dependent binding to DNA. May be involved in proper spermatogenesis by repressing the expression of genes unnecessary or incompatible with the maintenance of a haploid cell state (By similarity).
Pathway
Gene Expression; Generic Transcription Pathway;
Citations
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