Anti-ZFP36L1 (aa 1-108) polyclonal antibody

Species Reactivity

Human

Immunogen

ZFP36L1 (NP_004917, 1 a.a. ~ 108 a.a) partial recombinant protein with GST tag. The sequence is MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSS KFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGG

Conjugate

Alternative Names

ZFP36L1; ZFP36 ring finger protein-like 1; BRF1; ERF1; cMG1; ERF-1; Berg36; TIS11B; RNF162B; zinc finger protein 36, C3H1 type-like 1; EGF-response factor 1; butyrate response factor 1; early response factor Berg36; zinc finger protein 36, C3H type-like 1

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Pathway

Butyrate Response Factor 1 (BRF1) destabilizes mRNA; Regulation of mRNA stability by proteins that bind AU-rich elements;