YWHAH (AAH03047, 71 a.a. ~ 170 a.a) partial recombinant protein with GST tag. The sequence is MADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVFYLKMKGDY YRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHP
Conjugate
Unconjugated
Target
Alternative Names
YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; YWHA1; 14-3-3 protein eta; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide;
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5 UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
Pathway
Activation of BAD and translocation to mitochondria; Alpha6-Beta4 Integrin Signaling Pathway; Calcium Regulation in the Cardiac Cell; Cell cycle
Citations
Publication ()
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