General Notes
This product (Catalog No. DPABH-20636) is a rabbit-derived polyclonal antibody raised against human YTHDC1, targeting the amino acid region 360–709 of the protein. This antibody exhibits cross-reactivity with Human YTHDC1 from mouse and rat. It has been affinity purified by Protein A. YTHDC1, also named as KIAA1966 or YT521, is a 727 animo acid protein, which contains 1 YTH domain. YTHDC1 localizes in the nucleus and Interacts with EMD, KHDRBS1/SAM68, KHDRBS3, TRA2B/SFRS10, SC35 and SF2. YTHDC1 as a RNA-binding protein that regulates alternative splice site selection. The calcualted molecular weight of YTHDC1 is 85 kDa, but modified TFEB is about 110 kDa (PMID: 10973987 ).
DPABH-20636 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:500) applications.
DPABH-20636 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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