Rabbit Anti-Human Wnt5a Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant fusion protein of human WNT5A (NP_003383.2).

Conjugate

Application Notes

WB: 1:500-1:2000

General Notes

This product (Catalog No. DPABH-10959) is a rabbit-derived polyclonal antibody raised against human WNT5A. This antibody exhibits cross-reactivity with WNT5A from mouse and rat. It has been affinity purified by Protein A. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
DPABH-10959 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
DPABH-10959 is supplied as a liquid formulation in PBS with 0.02% sodium azide,50% glycerol,pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

hWNT5A; Wnt5a; WNT5A

Entrez Gene ID

UniProt ID