Anti-WRN monoclonal antibody (DCABH-1545) Knockout Validated

Rabbit anti-Human WRN monoclonal antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS7403
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to C-terminal amino acids of Human Werners syndrome helicase WRN.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
WRN; Werner syndrome, RecQ helicase-like; Werner syndrome; Werner syndrome ATP-dependent helicase; RECQ3; RECQL2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Regulation of Telomerase, organism-specific biosystem;

Citations


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References


Kawabe, Y; Seki, M; et al. Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1. JOURNAL OF BIOLOGICAL CHEMISTRY 275:20963-20966(2000).
Marciniak, RA; Lombard, DB; et al. Nucleolar localization of the Werner syndrome protein in human cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95:6887-6892(1998).

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