Anti-WRB (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Full length protein corresponding to amino acids 1-174 of Human Tryptophan rich protein (NP_004618.2).

Conjugate

Application Notes

WB: 1 μg/ml;

Alternative Names

WRB; tryptophan rich basic protein; CHD5; tail-anchored protein insertion receptor WRB; tryptophan-rich protein; tryptophan-rich basic protein; congenital heart disease 5 protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrom congenital heart disease.