Specifications
Species Reactivity
Mouse; Human
Immunogen
Purified recombinant fragment of Wnt1 expressed in E. coli.
Applications
Application Notes
WB: 1/500 - 1/2000; ELISA: 1/10000; IHC-P: 5 μg/ml;
Target
Alternative Names
WNT1; wingless-type MMTV integration site family, member 1; INT1; proto-oncogene Wnt-1; proto-oncogene Int-1 homolog; wingless-type MMTV integration site family, member 1 (oncogene INT1);
Product Background
Antigen Description
Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.
Pathway
Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Developmental Biology, organism-specific biosystem;
Citations
Publication ()
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COA
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