General Notes
This product (Catalog No. DPABH-23301) is a rabbit-derived polyclonal antibody raised against human WDR43, targeting the amino acid region 1–150 of the protein. It has been affinity purified by Protein A. WDR43, a WD40 domain-containing protein, is a conserved component of the small-subunit processome (SSUP), which mediates pre-18S ribosomal RNA (rRNA) transcription and processing in the nucleolus and is critical for ribosome biogenesis in yeast. Its mutation in zebrafish causes a variety of early developmental defects in specific tissues. WDR43 directly promotes ESC self-renewal by maintaining high-level expression of its target genes involved in pluripotency programs. (PMID: 28880863, 24497835, 31128943).
DPABH-23301 is suitable for use in Western blot (WB) (1:1,000–1:4,000), IHC (1:500–1:2,000) applications.
DPABH-23301 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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