General Notes
This product (Catalog No. DPABH-09149) is a rabbit-derived polyclonal antibody raised against human WBSCR17, targeting the amino acid region 1–126 of the protein. This antibody exhibits cross-reactivity with Human WBSCR17 from mouse and rat. It has been affinity purified by Protein A. WBSCR17, also known as GALNT17, which encodes a brain-expressed N-acetylgalactosaminyl transferase (GalNAcT), is located at the distal edge of a region that is commonly deleted or duplicated in Williams Beuren Syndrome (WBS), a developmental disorder with motor and coordination problems, impaired visuospatial memory, and abnormal social interaction (PMID: 31554716). WBSCR17 loss-of-function has significant effects on cerebellar development, and is associated with phenotypes including developmental delay, deficits in motor coordination, reduced exploratory activity, and impaired social behavior (PMID: 22787146). With the calculated molecular mass of recombinant WBSCR17 being 68 kDa, the 70-90-kDa glycoproteins could also be detected due to post-translational modifications (PMID: 22787146).
DPABH-09149 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:20–1:200) applications.
DPABH-09149 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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