Specifications
Immunogen
A synthetic peptide of human WARS2 is used for rabbit immunization.
Target
Alternative Names
WARS2; tryptophanyl tRNA synthetase 2, mitochondrial; tryptophan--tRNA ligase, mitochondrial; TrpRS; tryptophan tRNA ligase 2; mitochondrial; (Mt)TrpRS; tryptophan-tRNA ligase; tryptophan tRNA ligase 2, mitochondrial; tryptophanyl-tRNA synthetase, mitocho
Product Background
Antigen Description
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.
Pathway
Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Gene Expression, organism-specific biosystem; Mitochondrial tRNA aminoacylation, organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem;
Citations
Publication ()
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