Specifications
Species Reactivity
Mouse; Human; Monkey
Immunogen
Recombinant full length Human Breast cancer suppressor candidate 1 produced in HEK293T cells (NP_055437).
Applications
Application Notes
WB: 1/500 - 1/1000; Flow Cyt: 1/100; ICC/IF: 1/100;
General Notes
This antibody was produced by immunizing mice with full length recombinant human VWA5A expressed in HEK293T cell. VWA5A is expressed in various tissues, including the brain and endothelial cells, and may have a role in modulating the immune response and tissue repair. Due to its involvement in cellular processes, VWA5A is under investigation as a potential biomarker for certain cancers and autoimmune diseases.
Target
Alternative Names
VWA5A; von Willebrand factor A domain containing 5A; LOH11CR2A, loss of heterozygosity, 11, chromosomal region 2, gene A; von Willebrand factor A domain-containing protein 5A; BCSC 1; ortholog of mouse AW551984; breast cancer suppressor candidate 1; loss
Product Background
Antigen Description
May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Citations
Publication ()
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