Anti-VTI1A monoclonal antibody, clone 2F4

Antibody Isotype

IgG1

Clone

2F4

Species Reactivity

Human

Immunogen

Recombinant full length Human VTI1A produced in HEK293T cells (NP_660207)

Conjugate

Application Notes

WB: 1/4000;

Alternative Names

VTI1A; vesicle transport through interaction with t-SNAREs homolog 1A (yeast); vesicle transport through interaction with t-SNAREs homolog 1A; MVti1; Vti1 rp2; Vti1a; SNARE Vti1a-beta protein; vesicle transport v-SNARE protein Vti1-like 2; VTI1RP2; Vti1-r

Entrez Gene ID

UniProt ID

Antigen Description

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.

Pathway

SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem;