Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (N terminal)
Applications
Application Notes
WB: 1/1000 - 1/10000; Flow Cyt: 1/10 - 1/100.
Target
Alternative Names
VPS37C; vacuolar protein sorting 37 homolog C (S. cerevisiae); vacuolar protein sorting 37C (yeast); vacuolar protein sorting-associated protein 37C; FLJ20847; hVps37C; vacuolar protein sorting 37C; ESCRT-I complex subunit VPS37C;
Product Background
Antigen Description
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Pathway
Assembly of HIV virion, organism-specific biosystem; Disease, organism-specific biosystem; ESCRT-I complex, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Endosomal Sorting Complex Required For Transport (ESCRT), organism-specific biosystem; HIV Infection, organism-specific biosystem.
Citations
Publication ()
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COA
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