VIPR2 (NP_003373, 24 a.a. ~ 126 a.a) partial recombinant protein with GST tag. The sequence is ECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFY SKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILV
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase.
Pathway
G alpha (s) signalling events; GPCRs, Class B Secretin-like; Neuroactive ligand-receptor interaction; Signal Transduction
Citations
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