Specifications
Species Reactivity
Mouse; Rat; Dog; Human; Monkey
Immunogen
Recombinant full length Human Ube2G2 (amino acids 1-165) produced in HEK293T cells (NP_003334).
Applications
Application Notes
WB: 1/200 - 1/4000; IHC-P: 1/150; ICC/IF: 1/100;
Target
Alternative Names
UBE2G2; ubiquitin-conjugating enzyme E2G 2; ubiquitin conjugating enzyme E2G 2 (homologous to yeast UBC7) , ubiquitin conjugating enzyme E2G 2 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2 G2; UBC7; ubiquitin-protein ligase G2; ubiquitin carrier
Product Background
Antigen Description
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-48-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Citations
Publication ()
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COA
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