General Notes
This product (Catalog No. DPABH-12452) is a rabbit-derived polyclonal antibody raised against human UBA6, targeting the amino acid region 87–389 of the protein. This antibody exhibits cross-reactivity with Human UBA6 from mouse. It has been affinity purified by Protein A. UBA6(Ubiquitin-like modifier-activating enzyme 6) is also named as MOP4, UBE1L2 and belongs to the ubiquitin-activating E1 family. It probably acts as a single molecule like UBE1 and not as a heterodimeric E1 complex, as formed by AOS1/Uba2 and APP-BP1/Uba3. UBA6 is even more restricted in distribution because it is only found in vertebrates but not in lower organisms so that it might have a specialized role in tissues of higher organisms, and in particular, in the testis, where it is expressed by far most abundantly.(PMID:17580310). It has 4 isoforms produced by alternative splicing.
DPABH-12452 is suitable for use in Western blot (WB) (1:1,000–1:5,000), IHC (1:50–1:500), IF/ICC (1:50–1:500) applications.
DPABH-12452 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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