This product (Catalog No. DPABH-04876) is a rabbit-derived IgG polyclonal antibody raised against human USP46. This antibody exhibits cross-reactivity with USP46 from mouse and rat. It has been affinity purified by protein A. Ubiquitin-specific peptidase 46 (USP46) is a cysteine protease that acts as a deubiquitinating enzyme (DUB), playing a critical role in protein stabilization and cellular signaling. It regulates key processes such as Wnt/\(\beta \)-catenin signaling (via LRP6), glycolysis (via PGAM1), and neuronal activity, often functioning in complex with WDR48 and WDR20. DPABH-04876 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:100), IF (immunofluorescence) (1:50–1:100) applications. DPABH-04876 is supplied as a liquid formulation in PBS with 0.02% sodium azide, pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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