USP33 (NP_055832, 327 a.a. ~ 426 a.a) partial recombinant protein with GST tag. The sequence is SDRAENENGSRCFSEDNNETTMLIQDDENNSEMSKDWQKEKMCNKINKVNSEGEFDKDRD SISETVDLNNQETVKVQIHSRASEYITDVHSNDLSTPQIL
This gene encodes a deubiquinating enzyme important in a variety of processes, including Slit-dependent cell migration and beta-2 adrenergic receptor signaling. The protein is negatively regulated through ubiquitination by von Hippel-Lindau tumor protein (VHL). Alternative splicing results in multiple transcript variants and protein isoforms.
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