Rabbit Anti-Human UPK3B (a.a. 1-320) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human UPK3B protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-320 aa of BC004304

Conjugate

Application Notes

IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate
IHC: 1:500-1:2000

General Notes

This product (Catalog No. DPABH-11331) is a rabbit-derived polyclonal antibody raised against human UPK3B, targeting the amino acid region 1–320 of the protein. This antibody exhibits cross-reactivity with Human UPK3B from mouse. It has been affinity purified by Protein A. Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-3b (UPK3B), also named as p35, is a single-pass type I membrane protein. This protein dimerizes with uroplakin-1b (UPK1B) to exit out of endoplasmic reticulum, which is is an important early step in urothelial plaque assembly (PMID: 12446744).
DPABH-11331 is suitable for use in IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:500–1:2,000) applications.
DPABH-11331 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

P35; UP3b; UPIIIb; UPK3B; uroplakin 3B; Uroplakin IIIb

Entrez Gene ID

UniProt ID