Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ULK1 aa 450-550 (Cysteine residue). The exact sequence is proprietary.Database link: O75385
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/10000 - 1/50000;
Target
Alternative Names
ULK1; unc-51-like kinase 1 (C. elegans); unc 51 (C. elegans) like kinase 1; serine/threonine-protein kinase ULK1; ATG1; ATG1 autophagy related 1 homolog (S. cerevisiae); ATG1A; ATG1 autophagy related 1 homolog; autophagy-related protein 1 homolog; UNC51;
Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells.
Pathway
Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; Senescence and Autophagy, organism-specific biosystem; mTOR signaling pathway, organism-specific biosystem; mTOR signaling pathway, conserved biosystem;
Citations
Publication ()
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COA
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