Recombinant fragment corresponding to a region within amino acids 503 and 733 of Human UHRF1 (AAI13876)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/3000; ICC/IF: 1/100 - 1/1000.
Target
Alternative Names
UHRF1; ubiquitin-like with PHD and ring finger domains 1; E3 ubiquitin-protein ligase UHRF1; FLJ21925; ICBP90; Np95; RNF106; huNp95; nuclear protein 95; RING finger protein 106; transcription factor ICBP90; nuclear zinc finger protein Np95; inverted CCAAT
Putative E3 ubiquitin-protein ligase. May participate in methylation-dependent transcriptional regulation. Binds to inverted 5-CCAAT-3 box 2 in the TOP2A promoter, and activates TOP2A expression. Important for G1/S transition. May be involved in DNA repair and chromosomal stability.
Citations
Publication ()
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