Specifications
Immunogen
Synthetic peptide corresponding to residues within Human UGT2B15 (Uniprot ID P54855).
Applications
Application Notes
WB: 1/1000 - 1/10000.
Target
Alternative Names
UGT2B15; UDP glucuronosyltransferase 2 family, polypeptide B15; UDP glycosyltransferase 2 family, polypeptide B15; UDP-glucuronosyltransferase 2B15; UGT2B8; UDPGTh-3; UDPGT 2B15; UDP glycosyltransferase 2B15; UDP-glucuronosyltransferase 2B8; UDP-glucurono
Product Background
Antigen Description
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
Pathway
Ascorbate and aldarate metabolism, organism-specific biosystem; Ascorbate and aldarate metabolism, conserved biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem; Biological oxidations, organism-specific biosystem;
Citations
Publication ()
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COA
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