Anti-UGP2 monoclonal antibody, clone 4I4

Antibody Isotype

IgG2a

Clone

4I4

Species Reactivity

Human; Mouse; Rat

Immunogen

UGP2 (NP_001001521, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

UGP2; UDP-glucose pyrophosphorylase 2; UDP glucose pyrophosphorylase 1 , UGP1; UTP--glucose-1-phosphate uridylyltransferase; UGPP1; UDPGP; UGPase 2; UDP-glucose diphosphorylase; UDP-glucose pyrophosphorylase 1; UTP-glucose-1-phosphate uridyltransferase; U

Entrez Gene ID

UniProt ID

Antigen Description

The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene.

Pathway

Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem; Biological oxidations, organism-specific biosystem;