Synthetic peptide: C-PNHQGDGASQTSGE (with a Cysteine residue linker) corresponding to internal sequence amino acids 349-362 of Human Upstream Binding Protein 1 (NP_001121633.1, NP_055332.3.)
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 10 μg/ml.
Target
Alternative Names
UBP1; upstream binding protein 1 (LBP-1a); LBP1A; LBP1B; LBP-1B; LBP-1a; upstream-binding protein 1; transcription factor LBP-1;
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
Citations
Publication ()
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