KPC2 (Kip1 ubiquitylation-promoting complex 2) together with KPC1 forms the ubiquitin ligase KPC, which regulates degradation of the cyclin-dependent kinase inhibitor p27 at the G1 phase of the cell cycle. KPC2 contains a ubiquitin-like (UBL) domain, two ubiquitin-associated (UBA) domains, and a heat shock chaperonin-binding (STI1) domain.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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McNeill, H; Knebel, A; et al. A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs. BIOCHEMICAL JOURNAL 384:391-400(2004).
Mah, AL; Perry, G; et al. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. JOURNAL OF CELL BIOLOGY 151:847-862(2000).
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