General Notes
This product (Catalog No. DPABH-27598) is a rabbit-derived polyclonal antibody raised against human UAP1L1. It has been affinity purified by Protein A. UDP-N-acetylglucosamine pyrophosphorylase-1-like-1 (UAP1L1) is a protein that shares ~59% sequence identity with UDP-N-acetylglucosamine pryophosphorylase-1 (UAP1), which is directly involved in the synthesis of the sugar donor (UDP-GlcNac) for N-acetylglucosamine modification (O-GlcNAclation) of proteins in the cytoplasm, nucleus, and mitochondria, as well as for O- and N-linked protein glycosylation in the endoplasmic reticulum and the Golgi apparatus (PMID: 30097606, 35168617). Human UAP1L1 is also significantly upregulated in a distinct subset of HCC tissues and patients with upregulated expression of UAP1L1 appeared to have poor prognosis (PMID: 33987240).
DPABH-27598 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500), IF/ICC (1:20–1:200) applications.
DPABH-27598 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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