Anti-UAP1 monoclonal antibody, clone FQS21360

Antibody Isotype

IgG

Clone

FQS21360

Species Reactivity

Mouse; Rat; Human

Immunogen

A synthetic peptide, corresponding to residues in Human UAP1 (UniProt: Q16222).

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100; IP: 1/10 - 1/100; Flow Cyt: 1/100 - 1/500;

Alternative Names

UAP1; UDP-N-acteylglucosamine pyrophosphorylase 1; SPAG2; UDP-N-acetylhexosamine pyrophosphorylase; AgX; AGX1; antigen X; sperm associated antigen 2; sperm-associated antigen 2; AGX; AGX2;

Entrez Gene ID

UniProt ID

Antigen Description

Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

Pathway

Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Nucleotide sugar biosynthesis, eukaryotes, organism-specific biosystem.