Anti-TTLL8 (aa 37-67) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 37-67 of Human TTLL8 (UniProt A6PVC2).

Conjugate

Application Notes

WB: 1/100 - 1/500.

Alternative Names

TTLL8; tubulin tyrosine ligase-like family, member 8; protein monoglycylase TTLL8; tubulin--tyrosine ligase-like protein 8;

Entrez Gene ID

Antigen Description

Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction (By similarity).