Anti-TTK monoclonal antibody (DCABH-322)

Mouse anti-Human TTK monoclonal antibody for FC, ICC/IF, Dot, FuncS, IP, ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
O2
Species Reactivity
Human
Immunogen
Recombinant near full length protein (catalytically inactive - D663A), corresponding to amino acids 3-856 of Human Mps1.
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 2μg/106 cells; ICC/IF: 1 μg/ml; WB: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TTK; TTK protein kinase; dual specificity protein kinase TTK; cancer/testis antigen 96; CT96; MPS1L1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem;

Citations


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References


Nihira, K; Taira, N; et al. TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress. ONCOGENE 27:7285-7295(2008).
Tomizawa, K; Omori, A; et al. Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau. FEBS LETTERS 492:221-227(2001).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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