General Notes
This product (Catalog No. DPABH-28548) is a rabbit-derived polyclonal antibody raised against human TSPO, targeting the amino acid region 1–169 of the protein. This antibody exhibits cross-reactivity with Human TSPO from mouse. It has been affinity purified by Protein A. TSPO, also named Peripheral-type benzodiazepine receptor (PBR), encodes the translocator protein, belonging to tryptophan-rich sensory protein family. The protein is mainly localized in the outer mitochondrial membrane and expressed in steroid-synthesizing tissues (PMID:32881658, PMID:1326278). TSPO is involved in the translocation of cholesterol from the outer to inner mitochondrial membrane (PMID:21119734). In response to injury, TSPO has a upregulated expression in the peripheral nervous system (PMID:32423330, PMID:23251719). TSPO is also as a biomarker in a non-invasive procedure including detecting the inflammation in the heart and atherosclerotic plaques (PMID:24402571).
DPABH-28548 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500) applications.
DPABH-28548 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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