General Notes
This product (Catalog No. DPABH-03400) is a rabbit-derived polyclonal antibody raised against human TSPAN3, targeting the amino acid region 1–253 of the protein. This antibody exhibits cross-reactivity with Human TSPAN3 from mouse. It has been affinity purified by Protein A. Tetraspanin-3 (TSPAN3, also known as TM4SF8) is a member of the tetraspanin (TM4SF) family. Tetraspanins, so named because they contain four transmembrane domains, are frequently expressed at the cell surface in association with each other and with other molecules, and they function to regulate cell adhesion, migration, proliferation, and differentiation. TSPAN3 regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair. TSPAN3 is a glycosylated protein and it is differentially glycosylated in different tissues (PMID: 27818272).
DPABH-03400 is suitable for use in IHC (1:50–1:500), IF/ICC (1:50–1:500) applications.
DPABH-03400 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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