Anti-TSC22D3 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Full length protein corresponding to Human GilZ/ TilZ aa 1-200. Isoform 2.Sequence: MAQSKLDCRSPVGLDCCNCCLDLAHRSGLQRGSSGENNNPGSPTVSNFRQ LQEKLVFENLNTDKLNSIMRQDSLEPVLRDPCYLINEGICNRNIDQTMLS ILLFFHSASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELV EKNSQLERENTLLKTLAS

Conjugate

Application Notes

WB: 1 μg/ml;

Alternative Names

TSC22D3; TSC22 domain family, member 3; DIP; GILZ; hDIP; DSIPI; TSC-22R; TSC22 domain family protein 3; TSC-22-like protein; TSC-22 related protein; TSC-22-related protein; DSIP-immunoreactive peptide; DSIP-immunoreactive leucine zipper protein; delta sle

Entrez Gene ID

UniProt ID

Antigen Description

Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities.

Pathway

Ion channel transport; Transmembrane transport of small molecules;