General Notes
This product (Catalog No. DPABH-06348) is a rabbit-derived IgG polyclonal antibody raised against human TRIM24, targeting the amino acid region 901–1050 of the protein. This antibody exhibits cross-reactivity with TRIM24 from mouse, rat, dog, pig, horse, and rabbit. It has been affinity purified by Protein A. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
DPABH-06348 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-06348 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
TIF1A_HUMAN; Transcription intermediary factor 1-alpha; RNF82; TIF1; TIF1A; EC:2.3.2.27; TIF1-alpha; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; Tripartite motif-containing protein 24; tripartite motif containing 24; PTC6; TF1A; hTIF1; TIF1ALPHA; TIF1α
COA
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