Synthetic peptide within Mouse TREM2 aa 22-48 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. NP_112544.1.Database link: Q99NH8
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000.
Target
Alternative Names
TREM2; triggering receptor expressed on myeloid cells 2; TREM-2; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid c
May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
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