TOPBP1 (NP_008958, 1327 a.a. ~ 1435 a.a) partial recombinant protein with GST tag. The sequence is LLQSGGAKVLPGHSVPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYL MQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH
Conjugate
Unconjugated
Target
Alternative Names
TOPBP1; topoisomerase (DNA) II binding protein 1; TOP2BP1; DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-binding protein 1; DNA topoisomerase II-beta-binding protein 1;
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
Pathway
BARD1 signaling events;
Citations
Publication ()
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