This product (Catalog No. DPABH-20070) is a rabbit-derived polyclonal antibody raised against human TOM1L2, targeting the amino acid region 300–457 of the protein. This antibody exhibits cross-reactivity with Human TOM1L2 from mouse and rat. It has been affinity purified by Protein A. Target of Myb-like protein 2 (TOM1L2) acts as a MYO6/Myosin VI adapter protein that targets myosin VI to endocytic structures (PMID: 23023224). It may play a role in recruiting clathrin to endosomes and regulating growth factor-induced mitogenic signaling (PMID: 16412388; 16479011). TOM1L2 also regulates membrane trafficking that is linked to immunity and cell proliferation (PMID: 20604899). DPABH-20070 is suitable for use in Western blot (WB) (1:5,000–1:50,000), IHC (1:300–1:1,200), IF/ICC (1:50–1:500) applications. DPABH-20070 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Target Of Myb1 Like 2 Membrane Trafficking Protein; Target of Myb-like protein 2; TOM1-like protein 2
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