Anti-TMOD1 monoclonal antibody

Antibody Isotype

IgG2b

Clone

2G3

Species Reactivity

Human

Immunogen

Recombinant full length Human Tropomodulin 1 produced in HEK293 cells (NP_003266).

Conjugate

Unconjugated

Application Notes

WB: 1/500 - 1/2000; IHC-P: 1/50; Flow Cyt: 1/100; ICC/IF: 1/100;

Alternative Names

TMOD1; tropomodulin 1; D9S57E, TMOD; tropomodulin-1; ETMOD; E-Tmod; e-tropomodulin; erythrocyte tropomodulin; TMOD; D9S57E;

Entrez Gene ID

7111

UniProt ID

P28289

Antigen Description

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.

Pathway

Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem;

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More