Specifications
Immunogen
antigen sequence: PCNCLLICKD TSRRIGCPRP NCRRIINLGP VMLISEEQPA QPALPIQPEG TRVVCGHCGN TFLWMELRFN TLAKCPHCKK ISSVGSA, corresponding to amino acids 100-186 of Human TMEM55A.
Applications
Application Notes
IHC-P: 1/20 - 1/50.
Target
Alternative Names
TMEM55A; transmembrane protein 55A; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; ptdIns-4,5-P2 4-Ptase II; type 2 PtdIns-4,5-P2 4-Ptase; PtdIns-4,5-P(2) 4-phosphatase type II; type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase;
Product Background
Antigen Description
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.
Pathway
3-phosphoinositide degradation; D-myo-inositol-5-phosphate metabolism; superpathway of inositol phosphate compounds;
Citations
Publication ()
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COA
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