General Notes
This product (Catalog No. DPABH-22833) is a rabbit-derived polyclonal antibody raised against human TMEM258, targeting the amino acid region 1–54 of the protein. It has been affinity purified by Protein A. TMEM258, or transmembrane protein 258, is a component of the oligosaccharyltransferase (OST) complex. Research has shown that TMEM258 is involved in controlling ER stress and intestinal inflammation. In particular, it has been identified as a central regulator of intestinal homeostasis. The loss of TMEM258 leads to unresolved ER stress, which can result in apoptosis (PMID: 27974209). The calculated MW is 9 kDa, The observed MW is multiple bands, which may be caused by Glycosylation modification.
DPABH-22833 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:500) applications.
DPABH-22833 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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