A synthetic peptide of human TMED9 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
TMED9; transmembrane emp24 protein transport domain containing 9; p25; GMP25; HSGP25L2G; transmembrane emp24 domain-containing protein 9; p24alpha2; gp25L2 protein; glycoprotein 25L2; p24 family protein alpha-2;
TMED9 (transmembrane emp24 protein transport domain containing 9) is a protein-coding gene. Diseases associated with TMED9 include hereditary spastic paraplegia, and paraplegia. GO annotations related to this gene include protein binding. An important paralog of this gene is TMED4. Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.
Citations
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