Synthetic peptide corresponding to a region within N terminal amino acids 57-106 of Human TIPRL (NP_690866)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
TIPRL; TIP41, TOR signaling pathway regulator-like (S. cerevisiae); TIP41, TOR signalling pathway regulator like (S. cerevisiae); TIP41-like protein; dJ69E11.3; MGC3794; TIP41; type 2A-interacting protein; putative MAPK activating protein; putative MAPK-a
May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
Citations
Publication ()
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