Anti-TIMM8B (aa 1-83) polyclonal antibody

Species Reactivity

Human

Immunogen

TIMM8B (NP_036591, 1 a.a. ~ 83 a.a) partial recombinant protein with GST tag. The sequence is MAELGEADEAELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPGNRLDSRTENCLSSCV DRFIDTTLAITSRFAQIVQKGGQ

Conjugate

Alternative Names

TIMM8B; translocase of inner mitochondrial membrane 8 homolog B (yeast); DDP2; TIM8B; mitochondrial import inner membrane translocase subunit Tim8 B; DDP-like protein; deafness dystonia protein 2;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.[provided by RefSeq, Aug 2009]

Pathway

Metabolism of proteins;